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IRF1 anticorps

Cet anticorps anti-IRF1 est un anticorps Lapin Polyclonal détectant IRF1 dans WB et ELISA. Adapté pour Humain, Souris, Rat et Chien.
N° du produit ABIN2461650

Aperçu rapide pour IRF1 anticorps (ABIN2461650)

Antigène

Voir toutes IRF1 Anticorps
IRF1 (Interferon Regulatory Factor 1 (IRF1))

Reactivité

  • 83
  • 53
  • 34
  • 9
  • 9
  • 8
  • 7
  • 7
  • 6
  • 5
  • 4
  • 1
  • 1
  • 1
Humain, Souris, Rat, Chien

Hôte

  • 85
  • 8
  • 1
  • 1
Lapin

Clonalité

  • 77
  • 18
Polyclonal

Conjugué

  • 50
  • 10
  • 7
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp IRF1 est non-conjugé

Application

  • 79
  • 21
  • 18
  • 12
  • 12
  • 11
  • 7
  • 6
  • 4
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA
  • Purification

    Antibody is purified by peptide affinity chromatography method.

    Immunogène

    Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IRF1.
  • Indications d'application

    IRF1 antibody can be used for detection of IRF1 by ELISA at 1:62500. IRF1 antibody can be used for detection of IRF1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

    Concentration

    1 mg/mL

    Buffer

    Antibody is lyophilized in PBS buffer with 2 % sucrose.

    Conseil sur la manipulation

    As with any antibody avoid repeat freeze-thaw cycles.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    For short periods of storage (days) store at 4 °C. For longer periods of storage, store IRF1 antibody at -20 °C.
  • Antigène

    IRF1 (Interferon Regulatory Factor 1 (IRF1))

    Autre désignation

    IRF1

    Sujet

    IRF1 is interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.

    Poids moléculaire

    37 kDa

    ID gène

    3659

    NCBI Accession

    NP_002189

    UniProt

    P10914

    Pathways

    Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagy
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